METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL

  ... 正在查看此商品

  分享
Guaranteed Safe Checkout

Comprehensive Guide to METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL

Table of Contents

1. Product Overview & Specifications

Parameter Detail
CAS Number 220641-87-2
Chemical Formula C6H13NO·HCl
Molecular Weight 151.64 g/mol
Synonyms N-Methyl-tetrahydro-2H-pyran-4-amine hydrochloride
4-(Methylamino)tetrahydropyran HCl
Appearance White crystalline powder
Purity ≥96% (HPLC)
Packaging 1kg foil bags, 25kg fiber drums
Storage 2-8°C in dry environment

2. Key Applications & Industrial Uses

This heterocyclic amine hydrochloride derivative serves critical functions in:

  • Pharmaceutical intermediates for CNS drug development
  • Ligand synthesis in asymmetric catalysis
  • Building block for bioactive molecule construction
  • Precursor in agrochemical formulations
  • Chiral resolving agents in fine chemical production

3. Operational Guidelines

Handling Protocols:
Use NIOSH-approved respirators and neoprene gloves. Conduct operations under inert atmosphere (N2/Ar) when processing in solution phase.

Solubility Profile:

Solvent Solubility (mg/mL)
Water 82.3
Methanol 145.6
DCM 89.4

4. Comparative Analysis

Parameter THP-4-Methylamine HCl Piperidine Derivatives
Ring Strain Low (Chair conformation) Moderate
pKa 9.2±0.3 10.1±0.4
Thermal Stability Stable to 180°C Decomposes at 150°C

5. Client Implementation Case Studies

Case 1: CNS Drug Development
A Shanghai-based pharma company utilized this compound as a key intermediate in developing novel dopamine D3 receptor antagonists, achieving 92% yield in Buchwald-Hartwig amination steps.

Case 2: Catalytic Ligand Synthesis
German chemical researchers created chiral phosphine ligands using THP-protected amine groups, demonstrating 98% ee in asymmetric hydrogenation trials.

6. Procurement & Technical Support

For pricing, COA documentation, and bulk orders:

Our technical team provides:

  • Custom synthesis scale-up services
  • Regulatory compliance documentation
  • Application-specific formulation guidance
0.00
0 条评论
5
0
4
0
3
0
2
0
1
0
成为第一个评论 “METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL”

您的邮箱地址不会被公开。 必填项已用 * 标注

这是必填栏。

这是必填栏。

这是必填栏。

评论

目前还没有评论。

类别 
我的购物车
愿望清单
最近浏览
类别
Wait! before you leave…
Get 30% off for your first order
CODE30OFFCopy to clipboard
Use above code to get 30% off for your first order when checkout
比较产品 (0 产品)