User Guide for 1-(5-Bromo-pyridin-2-yl)-Ethanone: Applications, Case Studies & Technical Insights
Table of Contents
1. Product Overview & Specifications
| Parameter | 1-(5-Bromo-pyridin-2-yl)-Ethanone | Similar Compounds |
|---|---|---|
| CAS Number | 851368-76-8 | Varies by derivative |
| Molecular Formula | C₇H₆BrNO | C₇H₇NO (Pyridine analogs) |
| Purity | >98% (HPLC) | 90-95% typical |
| Melting Point | 92-95°C | 75-88°C (non-brominated) |
| Storage | 2-8°C inert atmosphere | Room temp (non-halogenated) |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate: Critical in synthesizing kinase inhibitors (e.g., JAK2/STAT3 pathway drugs).
Agrochemical Production: Precursor for pyridine-based pesticides with enhanced bioactivity.
Material Science: Building block for conductive polymers in OLED components.
3. Operational Guidelines & Best Practices
Reaction Conditions: Use anhydrous DMF as solvent at 0-5°C for bromination reactions.
Safety Protocols: PPE required due to lachrymatory properties (TLV: 0.1 ppm).
Purification: Column chromatography (silica gel, hexane/EtOAc 4:1) recommended.
4. Real-World Case Studies
Case 1: Optimized yield (82% → 91%) in anti-cancer drug intermediate synthesis through controlled bromine stoichiometry.
Case 2: Reduced reaction time by 40% in pesticide production via microwave-assisted synthesis.
5. Client Success Stories
Client A: Top 10 Pharma Co. achieved Phase II clinical trial material (CTM) production scale-up using our batch-certified material.
Client B: EU Agrochem Leader developed 3 patent-protected formulations using our GMP-grade stock.
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (50kg+ orders)
- Custom synthesis (modified pyridine derivatives)
- Regulatory support (REACH, TSCA documentation)
Email: info@vivalr.com
Tel: (86) 15866781826
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