Parameter | 2-Amino-3,5-dichloropyridine | Analogous Compounds |
---|---|---|
CAS Number | 4214-74-8 | 313535-01-2 (3,6-dichloro variant) |
Molecular Formula | C5H4Cl2N2 | C5H4Cl2N2 (isomeric differences) |
Melting Point | 81-83°C | 125°C (2,5-dichloro-3-aminopyridine) |
Water Solubility | Insoluble | Variable in halogenated analogs |
Application | Benefit | Typical Yield Improvement |
---|---|---|
Cross-coupling Reactions | Enhanced regioselectivity | 12-15% vs non-chlorinated analogs |
Catalytic Hydrogenation | Improved catalyst lifetime | 30-40 cycles stability |
Client | Application | Outcome |
---|---|---|
Shanghai Yuanye Bio-Tech | Antiviral drug intermediate synthesis | 15% cost reduction in final API |
Solarbio Science | High-purity analytical standards | 99.7% HPLC purity achieved |
Client: Shandong Chongcheng Energy
Challenge: Develop persistent fungicide with lower toxicity
Solution: 2-Amino-3,5-dichloropyridine based formulation
Results: 40% improved field efficacy, EPA Category IV certification
Client: Beijing Solarbio
Project: Scale-up novel kinase inhibitor
Role: Critical coupling reagent in lead compound
Achievement: Successful Phase I clinical trial material production
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