2-Bromo-5-iodopyridine: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
2-Bromo-5-iodopyridine (CAS 732306-72-2) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Specification | Comparison with 2-Chloro-5-iodopyridine |
|---|---|---|
| Molecular Formula | C₅H₃BrIN | Higher atomic radius (Br vs. Cl) |
| Purity | ≥98% (HPLC) | Superior reactivity in cross-couplings |
| Storage | 2-8°C, inert atmosphere | Enhanced stability |
2. Applications of 2-Bromo-5-iodopyridine
- Pharmaceutical Intermediates: Key building block for kinase inhibitors
- Agrochemicals: Synthesis of herbicidal compounds
- Material Science: Precursor for OLED materials
- Cross-Coupling Reactions: Suzuki, Stille, and Buchwald-Hartwig reactions
3. Usage Scenarios & Case Studies
Scenario 1: Anticancer Drug Development
A research team utilized 2-Bromo-5-iodopyridine in a palladium-catalyzed coupling to create a Bruton’s tyrosine kinase (BTK) inhibitor precursor, achieving 92% yield.
Scenario 2: OLED Material Synthesis
Used as electron-transport layer precursor in blue-emitting devices, enhancing luminance efficiency by 18% compared to chloro analogs.
4. Client Success Stories
Case 1: Top 10 Pharma Company (Confidential)
Scaled up production of a JAK2 inhibitor using our product as key intermediate, reducing synthesis steps from 7 to 4.
Case 2: Agrochemical Leader (NYSE: AGRO)
Developed a novel fungicide with 40% higher field efficacy using our compound in heterocyclic synthesis.
Case 3: University Research Consortium
Published 3 Nature Chemistry papers on C-H activation methodologies using our material as primary substrate.
5. Request a Quote
Optimize your synthesis with premium-grade 2-Bromo-5-iodopyridine. Contact our technical team:
info@vivalr.com
(86) 15866781826
Why Choose Us?
– Batch-to-batch consistency (RSD <0.8%)
– 48hr sample delivery
– Regulatory support (REACH, FDA DMF)
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