Chemical Name: Cysteamine hydrochloride
CAS No.: 156-57-0
Molecular Formula: C2H8ClNS
Molecular Weight: 113.61
Parameter | Specification |
---|---|
CAS Number | 156-57-0 |
Molecular Formula | C2H8ClNS |
Molecular Weight | 113.61 g/mol |
Appearance | White crystalline powder |
Melting Point | 128-130°C |
Solubility | Water: ≥50 mg/mL, Ethanol: Soluble |
Purity | ≥98% (HPLC) |
Feature | Cysteamine HCl | Cysteamine Bitartrate |
---|---|---|
Salt Form | Hydrochloride | Bitartrate |
Stability | High hygroscopicity | Improved stability |
Pharma Use | Cystinosis treatment | Limited applications |
Solubility Profile | Faster dissolution | Slower release |
Primary use in cystinosis therapy (orphan drug designation), antioxidant formulations, and radioprotective agents.
Intermediate in organosulfur compound production, catalyst in peptide synthesis, and corrosion inhibitor precursor.
Key reagent in studies of:
- Cellular redox mechanisms
- Lysosomal function analysis
- Heavy metal detoxification pathways
Dosage formulation guidance:
- Typical concentration: 50-150 mg/kg/day
- Compatibility with enteric coatings
- Stability testing protocols
Standard experimental preparation:
1. Prepare 0.1M PBS solution
2. Dissolve 25mg cysteamine HCl per ml
3. Filter-sterilize (0.22μm membrane)
4. Store at 2-8°C protected from light
Challenge: Required GMP-grade cysteamine HCl for phase III clinical trials
Solution: Supplied 25kg batches with 99.8% purity
Outcome: Accelerated FDA approval timeline by 18 months
Challenge: Needed custom particle size distribution (10-50μm)
Solution: Developed micronization process with 98% yield
Outcome: Enhanced dissolution rate by 40% in preclinical models
Request pricing/samples:
Email: info@vivalr.com
Phone: (86) 15866781826
Technical support available for:
- Regulatory documentation
- Stability studies
- Custom synthesis projects
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