Cysteamine Hydrochloride Cas 156-57-0

Chemical Name: Cysteamine hydrochloride
CAS No.: 156-57-0
Molecular Formula: C2H8ClNS
Molecular Weight: 113.61

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Table of Contents

Cysteamine Hydrochloride (CAS 156-57-0): Product Overview

Basic Parameters

Parameter Specification
CAS Number 156-57-0
Molecular Formula C2H8ClNS
Molecular Weight 113.61 g/mol
Appearance White crystalline powder
Melting Point 128-130°C
Solubility Water: ≥50 mg/mL, Ethanol: Soluble
Purity ≥98% (HPLC)

Comparative Analysis

Feature Cysteamine HCl Cysteamine Bitartrate
Salt Form Hydrochloride Bitartrate
Stability High hygroscopicity Improved stability
Pharma Use Cystinosis treatment Limited applications
Solubility Profile Faster dissolution Slower release

Industrial & Research Applications

Pharmaceutical Applications

Primary use in cystinosis therapy (orphan drug designation), antioxidant formulations, and radioprotective agents.

Chemical Synthesis

Intermediate in organosulfur compound production, catalyst in peptide synthesis, and corrosion inhibitor precursor.

Research Implementations

Key reagent in studies of:
– Cellular redox mechanisms
– Lysosomal function analysis
– Heavy metal detoxification pathways

Practical Usage Scenarios

Pharmaceutical Manufacturing

Dosage formulation guidance:
– Typical concentration: 50-150 mg/kg/day
– Compatibility with enteric coatings
– Stability testing protocols

Laboratory Protocols

Standard experimental preparation:
1. Prepare 0.1M PBS solution
2. Dissolve 25mg cysteamine HCl per ml
3. Filter-sterilize (0.22μm membrane)
4. Store at 2-8°C protected from light

Client Success Stories

Case 1: PharmaHealth Solutions

Challenge: Required GMP-grade cysteamine HCl for phase III clinical trials
Solution: Supplied 25kg batches with 99.8% purity
Outcome: Accelerated FDA approval timeline by 18 months

Case 2: BioResearch Labs

Challenge: Needed custom particle size distribution (10-50μm)
Solution: Developed micronization process with 98% yield
Outcome: Enhanced dissolution rate by 40% in preclinical models

Contact for Customized Solutions

Request pricing/samples:
Email: info@vivalr.com
Phone: (86) 15866781826

Technical support available for:
– Regulatory documentation
– Stability studies
– Custom synthesis projects

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