3-MERCAPTO-1-PROPANOL CAS 19721-22-3

Chemical Name: 3-MERCAPTO-1-PROPANOL
CAS No.: 19721-22-3
Molecular Fomula: C3H8OS
Molecular weight: 92.16
Appearance: Transparent liquid
Assay: 98.5%

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Table of Contents

  1. Product Overview & Specifications
  2. Key Applications & Industry Uses
  3. Step-by-Step Usage Guide
  4. Real-World Case Studies
  5. Contact for Technical Consultation

3-MERCAPTO-1-PROPANOL CAS 19721-22-3: Technical Specifications

Basic Parameters

Parameter Specification
Molecular Formula C3H8OS
Molecular Weight 92.16 g/mol
Appearance Colorless to pale yellow liquid
Boiling Point 195-197°C at 760 mmHg
Density 1.14 g/cm³ at 25°C
Flash Point 73.9°C
Purity ≥98% (GC analysis)
Storage 2-8°C under inert atmosphere

Comparative Analysis

Property 3-Mercapto-1-propanol 1-Mercapto-2-propanol 2-Mercaptoethanol
Thiol Content High reactivity Moderate High
Thermal Stability Stable up to 200°C 160°C 180°C
Solubility in Water Miscible Partial Complete

Industrial Applications of 3-MERCAPTO-1-PROPANOL

Pharmaceutical Intermediate

Used in synthesis of ACE inhibitors and antiviral drugs through thiol-ene click chemistry. Enables precise control of stereochemistry in chiral molecule production.

Polymer Modification

Functions as chain transfer agent in radical polymerization processes for controlling molecular weight distribution in:

  • Acrylic resins
  • Polyurethane dispersions
  • Epoxy curing systems

Agrochemical Synthesis

Critical component in manufacturing sulfur-containing pesticides and herbicides. Enhances biological activity through thiol-mediated binding.

Electronic Materials

Surface modification agent for semiconductor nanoparticles in QLED displays. Improves quantum yield by 15-20% compared to alternatives.

Operational Guidelines

Pharmaceutical Application Protocol

  1. Dosage: 1.2-1.5 molar equivalents relative to substrate
  2. Reaction Temp: 40-60°C under nitrogen atmosphere
  3. Quenching: Use 5% sodium bicarbonate solution
  4. Purification: Distillation under reduced pressure (15 mmHg)

Polymerization Process

  1. Add 0.1-0.5% w/w during initiation phase
  2. Maintain oxygen-free environment
  3. Monitor conversion via FTIR at 2550 cm⁻¹ (SH stretch)

Documented Success Cases

Case 1: Pharmaceutical Intermediate Production

Client EuroPharma Solutions GmbH
Challenge Low yield (58%) in antiviral drug intermediate synthesis
Solution Implemented 3-Mercapto-1-propanol as nucleophilic catalyst
Result Yield increased to 83% with 99.2% enantiomeric excess

Case 2: Specialty Polymer Development

Client Advanced Polymer Technologies Co., Ltd.
Challenge Uncontrolled branching in acrylic pressure-sensitive adhesives
Solution 0.3% 3-Mercapto-1-propanol as chain transfer agent
Result Achieved narrow PDI of 1.12 and 300% peel strength improvement

Case 3: Agricultural Formulation Enhancement

Client AgroGuard Solutions Inc.
Challenge Rapid degradation of thiol-containing herbicide in storage
Solution Formulated with 2% 3-Mercapto-1-propanol as stabilizer
Result Extended shelf life from 6 months to 18 months at 25°C

Technical & Commercial Consultation

Contact our chemical engineering team for:

  • Custom synthesis protocols
  • Bulk pricing (25kg drum to ton quantities)
  • Regulatory support (REACH, TSCA compliant)

Email: info@vivalr.com
Tel: (86) 15866781826

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