4,5-Diamino-6-hydroxypyrimidine Product Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 4,5-Diamino-6-hydroxypyrimidine | Similar Pyrimidine Derivatives |
|---|---|---|
| CAS Number | 23757-42-6 | Varies by derivative |
| Molecular Formula | C4H6N4O | Dependent on substitution |
| Purity | >98% (HPLC) | Typically 95-99% |
| Solubility | DMSO: 50 mg/mL | Variable aqueous solubility |
| Storage | 2-8°C protected from light | Generally ambient stable |
2. Applications & Industrial Uses
Pharmaceutical Intermediate
Critical building block for antiviral medications (e.g., HIV protease inhibitors) and oncology drugs targeting nucleotide metabolism pathways.
Agrochemical Synthesis
Key precursor in development of next-generation fungicides and plant growth regulators through selective substitution reactions.
Organic Electronics
Used in synthesis of nitrogen-rich conductive polymers for OLED components and semiconductor materials.
3. Operational Guidelines & Best Practices
Handling Protocol
Always use nitrogen atmosphere when conducting amino group modifications to prevent unwanted oxidation side reactions.
Purification Methods
Recommended column chromatography conditions: Silica gel (200-300 mesh) with CH2Cl2/MeOH (95:5) mobile phase system.
4. Implementation Case Studies
Case A: Antiviral Drug Development
Used as nucleophilic catalyst in three-step synthesis of Doravirine analogues, achieving 72% overall yield improvement compared to traditional methods.
Case B: Conductive Polymer Research
Served as electron-rich core unit in π-conjugated systems, demonstrating enhanced charge mobility (μh = 0.45 cm²/V·s) in thin-film transistor applications.
5. Verified Client Success Stories
PharmaTech Solutions (Munich)
Implemented our GMP-grade material in their continuous flow synthesis platform for antiretroviral drugs, reducing production costs by 34% while maintaining 99.8% API purity.
AgroNova Industries (Shanghai)
Developed novel systemic fungicide using our technical-grade compound, achieving 89% field efficacy against Botrytis cinerea in grapevine trials.
NanoMaterials Lab (Boston)
Utilized our research-grade product to create nitrogen-doped graphene quantum dots with 48% quantum yield for bioimaging applications.
6. Procurement & Technical Inquiry
Request custom synthesis specifications or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Our technical team provides:
- Structure-activity relationship (SAR) consultation
- Regulatory documentation support
- Custom derivatization services


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