4-Bromopyridine-2-carboxylic Acid: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
4-Bromopyridine-2-carboxylic Acid (CAS 114772-38-8) is a brominated pyridine derivative widely used in pharmaceutical synthesis, agrochemical research, and material science. Key specifications include:
| Parameter | Value |
|---|---|
| Molecular Formula | C6H4BrNO2 |
| Molecular Weight | 202.01 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
Comparative Advantages
- Superior reactivity in Suzuki-Miyaura couplings vs. non-brominated analogs
- Higher thermal stability compared to 3-bromo derivatives
- Enhanced solubility in polar solvents (DMSO, DMF)
2. Applications & Use Cases
Pharmaceutical Intermediates
Used in synthesizing kinase inhibitors and antiviral agents. The bromine atom enables efficient cross-coupling reactions for complex molecule assembly.
Agrochemical Development
Key precursor for herbicides and fungicides, particularly in creating pyridine-containing bioactive molecules.
Material Science
Building block for metal-organic frameworks (MOFs) and conductive polymers due to its chelating properties.
3. Industry Case Studies
Case 1: Anticancer Drug Development
Client: Top 10 Global Pharma Company
Application: Synthesis of PARP inhibitor intermediate
Result: 22% yield improvement vs. traditional routes
Case 2: Advanced Crop Protection
Client: EU Agrochemical Leader
Application: Novel fungicide synthesis
Result: Reduced reaction steps from 5 to 3
Case 3: OLED Material Research
Client: Asian Electronics Giant
Application: Electron-transport layer component
Result: Achieved 15% higher luminescence efficiency
4. Technical Support & Inquiry
Our team provides:
- Custom synthesis optimization
- Regulatory compliance documentation
- Bulk order coordination (50kg+ capacities)
Contact for Pricing/Samples:
Email: info@vivalr.com
Tel: (86) 15866781826
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