4-Bromopyridine-2-carboxylic acid

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4-Bromopyridine-2-carboxylic Acid: Comprehensive User Guide

1. Product Overview & Specifications

4-Bromopyridine-2-carboxylic Acid (CAS 114772-38-8) is a brominated pyridine derivative widely used in pharmaceutical synthesis, agrochemical research, and material science. Key specifications include:

Parameter Value
Molecular Formula C6H4BrNO2
Molecular Weight 202.01 g/mol
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder

Comparative Advantages

  • Superior reactivity in Suzuki-Miyaura couplings vs. non-brominated analogs
  • Higher thermal stability compared to 3-bromo derivatives
  • Enhanced solubility in polar solvents (DMSO, DMF)

2. Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesizing kinase inhibitors and antiviral agents. The bromine atom enables efficient cross-coupling reactions for complex molecule assembly.

Agrochemical Development

Key precursor for herbicides and fungicides, particularly in creating pyridine-containing bioactive molecules.

Material Science

Building block for metal-organic frameworks (MOFs) and conductive polymers due to its chelating properties.

3. Industry Case Studies

Case 1: Anticancer Drug Development

Client: Top 10 Global Pharma Company
Application: Synthesis of PARP inhibitor intermediate
Result: 22% yield improvement vs. traditional routes

Case 2: Advanced Crop Protection

Client: EU Agrochemical Leader
Application: Novel fungicide synthesis
Result: Reduced reaction steps from 5 to 3

Case 3: OLED Material Research

Client: Asian Electronics Giant
Application: Electron-transport layer component
Result: Achieved 15% higher luminescence efficiency

4. Technical Support & Inquiry

Our team provides:

  • Custom synthesis optimization
  • Regulatory compliance documentation
  • Bulk order coordination (50kg+ capacities)

Contact for Pricing/Samples:
Email: info@vivalr.com
Tel: (86) 15866781826

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