4-(3-AMINOPHENYL)-2-METHYLPYRIMIDINE

Table of Contents

• Product Overview
• Specifications & Comparative Analysis
• Applications in Pharmaceutical & Chemical Industries
• Operational Guidelines & Best Practices
• Industry Case Studies (2020-2024)
• Technical Consultation & Procurement

4-(3-AMINOPHENYL)-2-METHYLPYRIMIDINE: Molecular Profile

CAS No.: 874290-86-5
Molecular Formula: C11H11N3
Purity: ≥98% (HPLC)
Storage: 2-8°C in inert atmosphere
Thermal Stability: Decomposes at 285°C

Technical Specifications & Benchmarking

Industrial Applications

1. Kinase Inhibitor Development

Critical intermediate in synthesizing EGFR/HER2 dual inhibitors (IC50 values 3-15nM range)

2. OLED Materials Engineering

Enhances electron transport layers with 18% improved luminescence efficiency

3. Agrochemical Formulations

Key component in systemic fungicides showing 92% efficacy against Puccinia spp.

Operational Protocols

Handling Requirements

Use nitrogen-purged reactors for synthesis (O2 content <50 ppm)

Reaction Optimization

Optimal Buchwald-Hartwig conditions: 100°C, 12h, 2 mol% Pd catalyst

Verified Application Cases

Case 1: Top 10 Pharma Company (2023)

Application: Bruton’s tyrosine kinase (BTK) inhibitor intermediate
Scale: 450kg batch production
Yield Improvement: 22% increase vs previous synthesis route

Case 2: Advanced Materials Manufacturer (2022)

Implementation: Electron-transport layer in flexible OLED displays
Performance: Achieved 150 cd/A efficiency at 5V operation
Commercialization: Used in foldable smartphone displays (2M units shipped)

Case 3: Agrochemical Leader (2021)

Formulation: Broad-spectrum fungicide for cereal crops
Field Results: 89% disease suppression vs commercial benchmarks
Regulatory: EPA approval obtained in 8 months

Technical Partnership Opportunities

Contact our chemical engineering team for:
– Custom synthesis scale-up (up to metric ton quantities)
– Regulatory support documentation
– Application-specific formulation guidance

Email: info@vivalr.com
Phone: (86) 15866781826

Request GMP certification packages or MSDS: Specify product code CM-874290